what is chip seq analysis

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Updated on Oct 27, 2020

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what is chip seq analysis - ChIP-seq is a powerful method to identify genome-wide DNA binding sites for a protein of interest. Mapping the chromosomal locations of transcription factors (TFs), nucleosomes, histone modifications, chromatin remodeling enzymes, chaperones, and polymerases is one of the key tasks of modern biology. To this end, ChIP-seq is the standard methodology (Bailey et al., 2013). Multiple challenges presented in ChIP-seq are not only in sample preparation and sequencing but also in computational analysis.
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