TREM2

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Updated on Nov 12, 2018

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The protein encoded by this gene is a membrane protein that forms a receptor signaling complex with TYROBP. The encoded;protein may be involved in chronic inflammation by triggering the production of constitutive inflammatory cytokines.;Defects in this gene are a cause of polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy;(PLOSL).
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