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transgenic mice production

Agricultural Biotechnology

Updated on Apr 8, 2019

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Compared with conventional approaches, using transgenic animals can offer following advantages:

More robust antibody production (in vivo immune machinery compared to artificial engineering process)
Optimized properties due to in vivo selection and affinity maturation
No need for tedious and risky humanization and affinity improvement
Low immune tolerance to human antigens (rodent background)
Easy to operate
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