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tandem scfv production

Agricultural Biotechnology

Updated on May 7, 2018

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Tandem scFv-Fc BsAb is an IgG-like antibody with two single chain variable domains targeting distinct antigens. When constructing a Tandem scFv-Fc BsAb expression vector, genes coding each single-chain variable domain are tandem arrayed to a human Fc gene. Hence, the heterodimer that consists of these two chains is the desired bispecific antibody.
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