Stapled Peptide SynthesisPharmaceutical InformationUpdated on Jul 30, 2019 View more like this | Visit SHIRLEY, NY | Contact Cathy Miller |
Stapled peptide is a full-carbon scaffold with an α-helical structure. The all-carbon scaffold stabilizes the α-helical structure, enhances the interaction between the peptide molecule and the protein, and the peptide can pass through the cell membrane and is not easily hydrolyzed. Stapled peptides have higher physiological activity than previous small molecule drugs and protein analogs.
Advantages of Custom Stapled Peptides
• Better target affinity
• Increased proteolytic resistance and serum half- life
• Increased cell permeability
• Targeting of either extracellular or intracellular proteins
• Non-immunogenicity
• Viable pharmacokinetics and in vivo stability
Creative Peptides provides efficient and high quality peptide synthesis services while offering different modification services. Every step of peptide synthesis is subject to Creative Peptides’ stringent quality control. Typical delivery specifications include:
• HPLC chromatogram
• Mass spec analysis
• Synthesis report
• Certificate of Analyses
Advantages of Custom Stapled Peptides
• Better target affinity
• Increased proteolytic resistance and serum half- life
• Increased cell permeability
• Targeting of either extracellular or intracellular proteins
• Non-immunogenicity
• Viable pharmacokinetics and in vivo stability
Creative Peptides provides efficient and high quality peptide synthesis services while offering different modification services. Every step of peptide synthesis is subject to Creative Peptides’ stringent quality control. Typical delivery specifications include:
• HPLC chromatogram
• Mass spec analysis
• Synthesis report
• Certificate of Analyses
