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SLC9A3 Inhibitor

Chemicals Research

Updated on Aug 28, 2019

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An Overview of SLC9A3

SLC9A3 (Solute Carrier Family 9, subfamily A (NHE3, cation proton antiporter 3), member 3; region 5p15.3) gene encodes a protein that transports sodium ions and hydrogen. SLC9A3 protein plays a key role in pH regulation, functions from the elimination of acid produced by active metabolism, and plays a role in signal transduction, in which a chemical gradient of ions is emitted to absorb the sodium ions. Therefore, SLC9A3 is mainly responsible for maintaining the balance of sodium. SLC9A3 is mainly located in the renal membrane of the proximal end of the nephron and in the apical membrane of intestinal cells of the intestine.
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