Peptide BiomarkersAgricultural BiotechnologyUpdated on Nov 8, 2019 View more like this | Visit SHIRLEY, NY | Contact Creative Proteomics |
Currently two peptidomic approaches for biomarker discovery are under investigation: pattern recognition and mono-/oligo- biomarker detection. For the former, there is no need to obtain identity information of biomarker candidates, to designate patient samples with high specificity and sensitivity, solely based on the MS pattern.
Single/oligo biomarkers are more useful and reliable compared with the pattern recognition, because peptide differences in expression levels can be assigned and validated in biological samples collected from multiple sources. Mass spectrometry has a great potential to enter clinical chemistry. This analytical method is capable to reveal concentrations of analyte molecules simultaneously with an extraordinary high specificity, given by the precise macromolecular mass and sequencing capability.
Single/oligo biomarkers are more useful and reliable compared with the pattern recognition, because peptide differences in expression levels can be assigned and validated in biological samples collected from multiple sources. Mass spectrometry has a great potential to enter clinical chemistry. This analytical method is capable to reveal concentrations of analyte molecules simultaneously with an extraordinary high specificity, given by the precise macromolecular mass and sequencing capability.
