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US NY Suffolk County Shirley Pharmaceutical Laboratories

penicillin amidase

Pharmaceutical Laboratories

Updated on Jan 5, 2018

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The biosynthesis of Penicillin amidase in E. coli by hydrophobic protein chromatography is an inducible reaction which is regulated by metabolized carbon source (e.g. polyols, carboxylic acid etc.). It is also influenced by catabolite repression. It catalyzes the formation of amide bonds through an acyl-enzyme intermediate.
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