MHC peptide binding assay

Creative Biolabs offers SIAT ®in vitro class II HLA/MHC binding assay service that directly measures the affinity of predicted epitope peptide sequences to HLA alleles. The false positive and negative results generated by in silico models can, therefore, be eliminated. The information of immunogenic peptides identified by this assay is of great value in the development of novel biotherapeutic drugs. Based on the results of this assay, protein engineering strategies to deplete these T cell epitopes can be used to avoid side effects and the generation of anti-drug antibodies (ADAs). Learn more about MHC peptide binding assay.