Long Peptides SynthesisPharmaceutical InformationUpdated on Jan 14, 2019 View more like this | Visit SHIRLEY, NY | Contact Cathy Miller |
Synthesis challenges and strategies of long peptides
There are some challenges to the synthesis of long peptides, such as a large cumulative effect of yield, which can result in slow or incomplete coupling and/or reverse protection during the synthesis, as well as low solubility in the assembly of the protected peptide.
For the synthesis of long peptides, there are generally two ways of gradual growth and fragment condensation. The former starts with the starting amino acid (or peptide) and grows one amino acid per connection. The latter is obtained by condensation of a C-terminal protective peptide and an N-terminal protective peptide, and the new peptide chain with the sum of the two.
As one of the world's largest producers of synthetic peptides, Creative Peptides has developed a variety of proprietary technologies, peptide manufacturing facilities, and expertise that allow us to provide large volume, high quality and complex custom peptides from research grade to GMP production, and giving you the flexibility you need for custom peptides. Creative Peptides can provide long-chain peptides with certain amino acid sequences according to customer's requirements, ensuring high purity and high success rate synthesis, providing high quality long-chain peptide products for your research or production.
Available services:
Synthesis of long-chain peptides by peptide synthesis synthesizers and microwave reactors
Routine analysis after synthesis
MALDI-TOF MASS detection and identification
Report for qualify evaluation
Every step of peptide synthesis is subject to Creative Peptides’ stringent quality control. Typical delivery specifications include:
• HPLC chromatogram
• Mass spec analysis
• Synthesis report
• Certificate of Analyses
There are some challenges to the synthesis of long peptides, such as a large cumulative effect of yield, which can result in slow or incomplete coupling and/or reverse protection during the synthesis, as well as low solubility in the assembly of the protected peptide.
For the synthesis of long peptides, there are generally two ways of gradual growth and fragment condensation. The former starts with the starting amino acid (or peptide) and grows one amino acid per connection. The latter is obtained by condensation of a C-terminal protective peptide and an N-terminal protective peptide, and the new peptide chain with the sum of the two.
As one of the world's largest producers of synthetic peptides, Creative Peptides has developed a variety of proprietary technologies, peptide manufacturing facilities, and expertise that allow us to provide large volume, high quality and complex custom peptides from research grade to GMP production, and giving you the flexibility you need for custom peptides. Creative Peptides can provide long-chain peptides with certain amino acid sequences according to customer's requirements, ensuring high purity and high success rate synthesis, providing high quality long-chain peptide products for your research or production.
Available services:
Synthesis of long-chain peptides by peptide synthesis synthesizers and microwave reactors
Routine analysis after synthesis
MALDI-TOF MASS detection and identification
Report for qualify evaluation
Every step of peptide synthesis is subject to Creative Peptides’ stringent quality control. Typical delivery specifications include:
• HPLC chromatogram
• Mass spec analysis
• Synthesis report
• Certificate of Analyses
