library construction

Creative Biolabs can display the interest antibody in either scFv or Fab format to construct a high-quality antibody library. Due to the smaller size, scFv libraries are genetically more stable than Fab libraries, while Fab libraries lack the tendency to form higher molecular weight species, such as dimers and trimers, which can simplify the selection and characterization. Moreover, both human plasma cells and splenocytes from naïve or immune animals can be accepted as repertoire source for our antibody library construction service. In addition, Creative Biolabs is able to generate fully or semi-synthetic antibody libraries as well.