glucagon like peptides

Glucagon-like peptide-1(7–36) amide (GLP-1), a peptide secreted from intestinal enteroendocrine L cells, control systemic blood glucose homeostasis in humans after a meal. Therapies based on the GLP-1 are novel treatment options for type 2 diabetes that act through a variety of complementary mechanisms. Unlike other diabetes drugs, the insulinotropic effect of GLP-1 is self-limiting, as it falls once the plasma glucose level is lowered to normal range, reducing the risk of hypoglycemia. In addition, GLP-1 regulates postprandial glucose elevation through several other mechanisms, including promoting insulin gene transcription, stimulating pancreatic β-cell proliferation and neogenesis, inhibiting β-cell apoptosis, and blocking glucagon release.It also prevents gastric emptying and induces satiety, leading to body weight decrease.

Peptide-based diabetes mellitus treatment is leading a revolution in the treatment of diabetes due to their multi-functional properties. As the most thriving pharmaceutical companies pursue this booming field of research, it is necessary, more than ever, to have high quality cGMP (current Good Manufacturing Practice) peptides synthesis. Creative Peptides is one of the primary suppliers of diabetes related peptides with a range of more than 100 peptides, from milligrams to kilograms, generic standard to cGMP standard. As a reliable partner for GMP grade peptides manufacture, we have served a great many of customers by providing high quality peptides (≥99%) for their projects.

Please check our list of some of the diabetes related peptides we offer. To request pricing please feel free to contact us at [email protected]. Can't find the item you are looking for? Please inquire.