fatty acid analysis

In the last few decades, it is shown that SCFAs play an important role in the prevention and treatment of a series of metabolic syndrome such as bowel disorders and some cancer. In some clinical studies, the administration of SCFAs can enhance the therapeutic efficacy of some immunological intestinal disorders like Crohn's disease, ulcerative colitis, and antibiotic-associated diarrhea, though the mechanism remains to be determined. It is indicated that SCFAs potently benefit mammalian energy metabolism, with the underlying mechanisms of intensive research interest. The excessive energy intake and lack of physical exercise result in a series of metabolic syndrome such as hypertension, obesity, dyslipidemia and loss of glycemic control. It is shown in epidemiological studies that higher dietary fibers intake will benefit body weight, food intake and glucose homeostasis and reduce the risk of metabolic disorders such as diabetes, cardiovascular disease, irritable bowel syndrome, inflammatory bowel disease, and colon cancer. That’s because dietary fibers are fermented by gut bacteria in the cecum and large intestine and produce SCFAs, which are beneficial.