Enolase InhibitorPharmaceutical InformationUpdated on Apr 11, 2019 View more like this | Visit SHIRLEY, NY | Contact BOCSCI INC |
BOC Sciences offers Enolase Inhibitors for research use.
Major types of enolase
There are three isozymes of enolase: alpha-enolase (ENO1), beta-enolase (ENO3), gamma-enolase (NSE). Alpha-enolase is localized in all foetal and in the majority of adult mammal tissues. Beta-enolase is muscle-specific, and gamma-enolase is neuron-specific. NSE is a marker for neurons and peripheral neuroendocrine cells that exist as either γγ or αγ dimeric isozymes. While the γγ form of NSE is mainly expressed in neurons, the αγ form is expressed in microglia, oligodendrocytes, and astrocytes. In mammals, the three isoenzymes are encoded by independent loci. All enolase isoforms have a molecular range between 82 and 100 kDa and share high homology and kinetic properties.
Major types of enolase
There are three isozymes of enolase: alpha-enolase (ENO1), beta-enolase (ENO3), gamma-enolase (NSE). Alpha-enolase is localized in all foetal and in the majority of adult mammal tissues. Beta-enolase is muscle-specific, and gamma-enolase is neuron-specific. NSE is a marker for neurons and peripheral neuroendocrine cells that exist as either γγ or αγ dimeric isozymes. While the γγ form of NSE is mainly expressed in neurons, the αγ form is expressed in microglia, oligodendrocytes, and astrocytes. In mammals, the three isoenzymes are encoded by independent loci. All enolase isoforms have a molecular range between 82 and 100 kDa and share high homology and kinetic properties.
