Endocannabinoids

Because of their low abundance and structural variability, the quantification of endogenous endocannabinoid is challenging. LC–MS/MS platform enable simultaneous relative and absolute quantification of multiple metabolites in this pathway. The results are widely used for investigating the relative changes in metabolite concentrations, and potential biomarker discovery. Creative Proteomics has established sensitive, reliable, and accurate HPLC-MS/MS method for quantification of endocannabinoid metabolites.