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Degrasyn

Chemicals Research

Updated on Oct 10, 2016

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Degrasyn, also known as WP1130, is a small molecule that specifically and rapidly down-regulates both wild-type and mutant Bcr/Abl protein without affecting bcr/abl gene expression in chronic myelogenous leukemia (CML) cells and Hsp90/Hsp70 ratios within the cells.
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