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CYP450 Metabolites

Agricultural Biotechnology

Updated on Mar 11, 2020

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The CYP2C family is involved in the production of EETs. Specific examples of this family include a CYP2C11 enzyme present in astrocytes in the brain, CYP2C8 and 2C9 in human liver and endothelial cells, 2C2 in rabbit kidney, CYP2C29, 2C38 and 2C39 in the liver, kidney and brain of mice and CYP2C23 in the kidney of rats. Also CYP1A, 2B and 2J catalyze the formation of EETs in various tissues. The formation in various tissues is highly dependent on experimental conditions.
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