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Cyclic Peptide synthesis

Pharmaceutical Information

Updated on Dec 11, 2018

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Cyclic peptide compounds are a class of cyclic compounds with special structure, widely biological activity and unique mechanism of action, which play an important role in natural products. Cyclic peptides are compounds of stable and uniform conformation in peptide molecules, which have high selective affinity for receptors, strong metabolic stability, and high oral availability. As a drug molecule, a cyclic peptide compound has a wide range of biological activities such as anticancer, antiviral, antibacterial, antifungal, and enzyme inhibitors. Therefore, research on cyclic peptide drugs is receiving more and more attention.

Cyclic peptide synthesis has proven to be useful for several applications:

Structural studies of peptides
Investigation of peptides and their biological function
Enzyme function and kinetics
Cyclic peptides can be produced chemically by using solid-phase peptide synthesis, enzymatic chemistry, or expressed in microorganisms using DNA recombinant techniques. The team of the Creative Peptides insist on continuous innovation, using amide bonds, disulfide bonds and multiple oxidation bridges to synthesize various cyclic peptides to meet the different needs of customers.
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