Chemokines

The chemokine family of proteins has broad, diverse functional repertoires. However, their structural variation is narrow. Chemokines are small (8-10 kDa), secreted single polypeptide chains 70-100 residues long. Across the family, the proteins have 20-95% amino acid sequence identity (including conserved cysteine residues) and new members are continuing to be identified at a rapid pace;