CD38

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Updated on Mar 22, 2017

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CD38 (cluster of differentiation 38), also known as cyclic ADP ribose hydrolase, is a transmembrane glycoprotein found on the surface of some immune cells including plasma cells, activated or immature T and B cells, monocytes, and natural killer cells. CD38 participates in cell adhesion, signal transduction and calcium signaling. It is expressed at high levels in the plasma cell tumor, prostate cancer, stomach cancer, and neuroblastoma. CD38 is used as one of the plasma cell markers and its ligand is CD31 molecules.
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