Baculovirus expression vector system

Baculoviruses are arthropod-specific viruses that contain large double-stranded circular DNA genomes of 80,000-180,000 bp. Baculovirus strains are highly species-specific and cannot propagate in any non-invertebrate host. The Baculovirus genome is replicated and transcribed in the nuclei of infected host cells where the large baculovirus DNA is packaged into rod-shaped nucleocapsids.