Samantha is an unincorporated community in Tuscaloosa County, Alabama, United States. Samantha is located along U.S. Route 43, north of Tuscaloosa. Samantha has a post office with ZIP code 35482. Samantha was named in honor of the wife of the first postmaster, Sylvester Monroe Cowden.
Notable people
Dan Boone, Major League Baseball pitcher
Ike Boone, Major League Baseball player
