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Holiday Inn Express & Suites St. Louis South - I-55 by IHG

Updated on Jul 20, 2026

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Holiday Inn Express & Suites St. Louis South - I-55 by IHG

Hotels.com logo Lowest Price $148.34 Get Booking Details

Map image for 4250 Midamerica Lane SAINT LOUIS, MO
Located in: SAINT LOUIS, MO
Along with an indoor pool, this smoke-free hotel has a 24-hour fitness center and a business center. Free buffet breakfast, free WiFi in public areas, and free self parking are also provided. Additionally, a 24-hour front desk, a front-desk safe, and a banquet hall are onsite.
Housekeeping is available on request.
Holiday Inn Express & Suites St. Louis South - I-55 by IHG offers 99 accommodations with safes and coffee/tea makers. 49-inch flat-screen televisions come with cable channels. Guests can make use of the in-room refrigerators and microwaves. Bathrooms include complimentary toiletries and hair dryers.

Guests can surf the web using the complimentary wired and wireless Internet access. Business-friendly amenities include desks and phones; free local calls are provided (restrictions may apply). Additionally, rooms include irons/ironing boards and blackout drapes/curtains. Change of towels and change of bedsheets can be requested. Housekeeping is provided daily.


Recreational amenities at the hotel include an indoor pool and a 24-hour fitness center.
Located in St. Louis, Holiday Inn Express & Suites St. Louis South - I-55 by IHG is in the business district. Arnold Historical Society & Museum and Jefferson Barracks Historic Park are cultural highlights, and some of the area's landmarks include Missouri Civil War Museum and Ulysses S. Grant National Historic Site. Ready for a night out? Consider Das Bevo and Casa Loma Ballroom.
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Popular amenities
  • ac
  • breakfast included
  • business services
  • crib
  • elevator
  • fitness equipment
  • free parking
  • frontdesk 24 hour
  • heater
  • housekeeping
  • internet
  • microwave
  • no smoking
  • pool
  • tv
Property amenities
Food and Drink
  • Free buffet breakfast available daily 6:00 AM–9:30 AM
Internet
  • Available in all rooms: Free WiFi and wired Internet
  • Available in some public areas: Free WiFi
Parking
  • Free self parking on site
  • Wheelchair-accessible parking and van parking available
Things to do
  • 24-hour fitness center
  • Indoor pool
Family Friendly
  • Free cribs/infant beds
  • Indoor pool
  • Microwave
  • Refrigerator
Conveniences
  • Banquet hall
  • Elevator
  • Front-desk safe
  • Vending machine
Guest Services
  • 24-hour front desk
  • Change of bedsheets (on request)
  • Change of towels (on request)
  • Daily housekeeping
Business Services
  • Business center
  • Meeting rooms
Outdoor
  • Pool sun loungers
Language Spoken
  • English
Accessibility
  • Elevator
  • If you have requests for specific accessibility needs, please contact the property using the information on the reservation confirmation received after booking.
  • Stair-free path to entrance
  • Visual alarms in hallways
  • Well-lit path to entrance
  • Wheelchair-accessible concierge desk
  • Wheelchair-accessible fitness center
  • Wheelchair-accessible lounge
  • Wheelchair-accessible parking
  • Wheelchair-accessible path of travel
  • Wheelchair-accessible path to elevator
  • Wheelchair-accessible pool
  • Wheelchair-accessible public washroom
  • Wheelchair-accessible van parking
More
  • No plastic drinking straws
  • Smoke-free property
Room amenities
Bedroom
  • Air conditioning (climate-controlled)
  • Bed sheets
  • Blackout drapes/curtains
  • Free cribs/infant beds
  • Heating
Bathroom
  • Free toiletries
  • Hair dryer
  • Private bathroom
  • Shampoo
  • Soap
  • Toilet paper
  • Toothbrush and toothpaste (on request)
  • Towels
Entertainment
  • Cable channels
  • 49-inch flat-screen TV
Food and Drink
  • Coffee/tea maker
  • Microwave
  • Refrigerator
More
  • Connecting rooms available
  • Desk
  • Free local calls
  • Iron/ironing board
  • Laptop-friendly workspace
  • Phone
  • Safe
Policies
Check-in
  • Check-in start time: 3:00 PM; Check-in end time: 2:30 AM
  • Minimum check-in age: 21
Check-out
  • Check-out before 11 AM
  • Contactless check-out available
Pets
  • Pets not allowed (service animals are welcome, and are exempt from fees)
Special check-in instructions
  • Extra-person charges may apply and vary depending on property policy
  • Government-issued photo identification and a credit card, debit card, or cash deposit may be required at check-in for incidental charges
  • Safety features at this property include a fire extinguisher
  • Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
  • This property accepts credit cards; cash is not accepted
  • This property affirms that it follows the cleaning and disinfection practices of Clean Promise (IHG)
Property payment types
  • American Express
  • Diners Club
  • Discover
  • JCB International
  • Mastercard
  • Visa
Important Information
You need to know
  • Extra-person charges may apply and vary depending on property policy
  • Government-issued photo identification and a credit card, debit card, or cash deposit may be required at check-in for incidental charges
  • Safety features at this property include a fire extinguisher
  • Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
  • This property accepts credit cards; cash is not accepted
  • This property affirms that it follows the cleaning and disinfection practices of Clean Promise (IHG)
We should mention
  • Pool access available from 8 AM to 10 PM
  • The property has connecting/adjoining rooms, which are subject to availability and can be requested by contacting the property using the number on the booking confirmation
  • This property welcomes guests of all sexual orientations and gender identities (LGBTQ+ friendly)
 

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