NGS-Based RNA-Sequencing Market : Emerging Trends, Innovations, Key Industry Insights and Opportunities

Extensive primary research was conducted after acquiring a preliminary understanding of the global NGS-based RNA-sequencing market scenario through secondary research. Primary interviews were conducted with market experts from both the demand-side (companies providing sequencing services, cancer research laboratories, hospitals, research universities, and government laboratories, among others) and supply-side respondents (NGS platform manufacturers, NGS reagent & consumables providers and distributors, among others) across North America, Europe, the Asia Pacific, Latin America, and the Middle East & Africa. 

Expected Revenue Growth:
 
 The NGS-based RNA-sequencing industry size is projected to reach USD 4.2 billion by 2024 from USD 1.7 billion in 2019, at a CAGR of 20.0% during the forecast period.
 
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Key Factors Driving Market Growth:
 
 Market growth is driven mainly by the advantages of RNA-seq over conventional technologies; an increasing number of RNA-seq grants; rising number of research activities involving RNA-seq; and rapid growth in precision medicine market.

 The expression profiling analysis segment accounted for the largest share of the NGS-based RNA-sequencing industry, by application, in 2018
 
Based on application, the NGS-Based RNA-Sequencing Market is segmented into expression profiling analysis, small RNA sequencing, De Novo transcriptome assembly, and variant calling & transcriptome epigenetics. In 2018, the expression profiling analysis segment accounted for the largest share of the RNA Sequencing Market. The dominant market position of this segment is attributed mainly to the increasing prevalence of metabolic disorders, multiple sclerosis, and other diseases. These factors will continue to propel the demand for expression profiling analysis to provide specific treatment options in the RNA Sequencing market during the forecast period.
 
The nanopore segment is expected to register the highest growth in the NGS-based RNA-sequencing market, by type, during the forecast period
 
 Based on technology, the NGS-based RNA-sequencing industry is segmented into sequencing by synthesis, ion semiconductor sequencing, single molecular real-time sequencing, and nanopore sequencing. Nanopore sequencing technology registers the highest growth rate in the market as it is the only sequencing technology with direct RNA sequencing capabilities and facilitates sequencing of full-length RNA strands and modified RNA nucleotides using a simple library prep, without the need of conversion to double-stranded DNA.
 
North America dominated the NGS-based RNA-sequencing market
 
North America accounted for the largest share of RNA Sequencing market in 2018. The large share of this region is the growing prevalence of target diseases, government support through funds for genomics research, advancements in RNA-Seq products, increasing research on cancer & inherited rare diseases, and the strong presence of key players such as Illumina (US), Thermo Fisher (US), and Agilent Technologies (US) in this region.
 
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Key Players:
 
Illumina (US), Thermo Fischer Scientific (US) and Oxford Nanopore (UK), Agilent Technologies, Inc. (US), BGI (China), PerkinElmer Inc. (US), QIAGEN (Germany), Eurofins Scientific (Luxembourg), F. Hoffmann-La Roche Ltd (Switzerland), Takara Bio Inc. (Japan), GENEWIZ, Inc. (US), Hamilton Company (US), Macrogen (South Korea), Zymo Research (US), and Tecan Genomics, Inc. among others are the major players operating in the NGS-based RNA-sequencing market.