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Alzheimer’s Treatment with Stem Cells
Since the successful acquisition of human embryonic stem cells in 1998, scientists have begun to study the treatment of Alzheimer’s disease (AD) with stem cells. The possible mechanisms of stem cell therapy for AD include repairing and replacing damaged neurons, reconstructing neural circuits and functions, secreting trophic factors, and inhibiting amyloid protein formation. Using stem cells to treat AD is rapidly gaining momentum and considered to be the most potential treatment option for radical curing of this disease, as animal model-based researches indicate optimistic results, in addition, the world’s first stem cell drug derived from mesenchymal stem cells has been approved for the treatment of AD. Nonetheless, it is necessary to study the safety and efficacy of stem cell therapy prior to human clinical trials.
Since the successful acquisition of human embryonic stem cells in 1998, scientists have begun to study the treatment of Alzheimer’s disease (AD) with stem cells. The possible mechanisms of stem cell therapy for AD include repairing and replacing damaged neurons, reconstructing neural circuits and functions, secreting trophic factors, and inhibiting amyloid protein formation. Using stem cells to treat AD is rapidly gaining momentum and considered to be the most potential treatment option for radical curing of this disease, as animal model-based researches indicate optimistic results, in addition, the world’s first stem cell drug derived from mesenchymal stem cells has been approved for the treatment of AD. Nonetheless, it is necessary to study the safety and efficacy of stem cell therapy prior to human clinical trials.
