Clifton is an unincorporated town, a post office, and a census-designated place (CDP) located in and governed by Mesa County, Colorado, United States. The CDP is a part of the Grand Junction, CO Metropolitan Statistical Area. The Clifton post office has the ZIP Code 81520. At the United States Census 2010, the population of the Clifton CDP was 19,889, while the population of the 81520 ZIP Code Tabulation Area was 13,447.
The Clifton Post Office has been in operation since 1900. The community was named for cliffs near the town site.
The Clifton CDP has an area of , including of water.
The United States Census Bureau initially defined the for the